it’s been four months since i last took a cymbalta and, a lifetime or several since the horrific trudge and crawl that has been cymbalta withdrawal.
tinnitus remains and i occasionally get a visit of bowling ball head but the most detrimental dropping of the experience is a depression…devastatingly deep and dark.
i wonder, when i can muster the initiative for such an ambitious endeavor, about the potential of permanent alteration to my body’s ability to produce and use serotonin and norepinephrine. these chemicals affect mood. cymbalta inhibits the re-uptake of these two brain messengers thereby causing an accumulation and increasing the amount present in the brain. cocaine works this way by inhibiting the re-uptake of dopamine.
neither cymbalta nor cocaine create additional neurotransmitters but rather inhibit what’s there from being taken away, as it would in the natural process. over time the body will decrease the amount it produces if there is enough present; its process is likely to atrophy if it determines a decreasing lack of demand to create more. in time cocaine users need more cocaine because the brain reduces the amount of dopamine it produces and the way to get more is to further reduce the re-uptake to maintain the feeling that dopamine induces.
thing is, the body can be helped to increase the amount of neurotransmitters it makes by simply providing the materials – nutrients! directly and indirectly, the body converts the essential amino acid tryptophan and non-essential tyrosine into serotonin and norepinephrine respectively. both aminos are part of the proteins of fish, eggs and meat. tryptophan is also found in chocolate, spirulina and sesame seeds. passionfruit and papaya can increase tyrosine production.
so, why in the hell would a dr. prescribe a two-hundred-dollar-a-month drug to trick the brain into hanging on to used neurotransmitters?
greed and horseshit. for example:
tryptophan was available as a supplement until it was banned by the FDA on March 22, 1990. the process to produce it, by a particular supplier, was contaminated and consequently twenty-seven Americans who ingested it died and fifteen hundred others were disabled. the process, not the nutrient, was the cause.
on March 26, 1990, four days after the tryptophan ban by the FDA, Newsweek’s feature article was about eli lilly’s serotonin re-uptake inhibitor, Prozac (“Prozac: A Breakthrough Drug for Depression”).